dna pol

Evidence also shows that DNA polymerase mu ( pol μ) is only present in mammals, and is a duplicated gene of terminal deoxynucleotidyl transferase ( TdT).

DNA聚合酶mu（polμ）基因仅存在于哺乳动物基因组中，是脱氧核苷酸末端转移酶（TdT）的重复基因；

DNA pol β Gene Mutation in Esophageal Carcinoma

食管癌中DNA聚合酶β的突变

Results: Higher expression of DNA pol β mRNA, Fas mRNA and lower expression of p53 mRNA in all of brain tumors were found compared with those in normal adjacent cancer tissue ( P < 0.01).

结果：与相应瘤旁正常脑组织相比，脑胶质瘤及良性脑肿瘤组织中DNA polβ、Fas基因mRNA高表达，p53基因mRNA低表达（P均

Methods Twenty-six cases of nasopharyngeal carcinoma tissues and control epithelial tissues were collected to study DNA pol β gene mutation with PT-PCR, PCR-SSCP and DNA sequence analyzing technique.

方法采用RT-PCR法（逆转录DNA聚合酶链反应）、PCR SSCP（聚合酶链单链构象多态性分析）、DNA序列分析法对26例鼻咽癌组织及癌旁组织标本进行polβ基因突变研究。

The construction and identification of recombinant eukaryotic expression vector containing specific mutant DNA pol β gene derived from prostate cancer

前列腺癌特异突变DNA聚合酶β真核表达载体构建及鉴定

Molecular mechanism of DNA pol β in DNA repair

DNA聚合酶β在DNA修复作用中的分子机制

Expression of p53 Gene with DNA pol β and CMV Promoter in Salivary Adenoid Cystic Carcinoma Cells

DNA polβ启动子和CMV启动子调控的p53基因在涎腺腺样囊性癌细胞中表达的比较

DNA polymerase B ( pol B) is the key enzyme for single base excision repair.

DNA聚合酶β（polymeraseβ，polβ）主要是单个碱基切除修复中的关键酶之一。

The expression of DNA pol β mRNA and protein in the A549/ TXL20 cells were significantly higher than those in A549 cells.

A549/TXL20细胞中DNA polβmRNA及蛋白的表达水平均高于A549细胞（P

DNA pol β Gene Mutation in Esophageal Carcinoma RNA POLYMERASE ACTIVITY OF NUCLEI ISOLATED FROM LEAVES OF VICIA FABA

食管癌中DNA聚合酶β的突变分离的蚕豆细胞核的RNA聚合酶活力的研究

Conclusion: The high expression of DNA pol β mRNA, Fas mRNA and low expression of p53 mRNA may be related to the carcinogenesis and development of brain tumors and their malignant degree.

结论：p53基因mRNA低表达及DNA polβ和Fas基因mRNA高表达与脑肿瘤的发生发展及恶性程度有关。

Analysis reveals that DNA Polymerase beta ( pol β) in eukaryon may be of viral origin.

分析显示：真核生物DNA聚合酶beta（polβ）可能起源于病毒基因的水平转移；

Methods: By using RT PCR, SSCP, analysis of DNA sequence, the mutations of DNA pol β gene in 25 cases of human esophageal cancer and the adjacent tissues from non high incidence area were tested.

方法：利用RT PCR、SSCP及DNA序列分析的方法，对河南省非食管癌高发区25例食管癌及其癌旁组织中聚合酶β基因的变异情况进行分析。

[ Conclusions] The A549/ TXL20 cell line shows drug resistant phenotype and may be related to overexpression of DNA pol β.

结论A549/TXL20具有多药耐药表型，耐药性产生可能与细胞内DNA polβ表达增高有关。